When you supplement with DIM, it works to prevent the bad estrogen pathways and strengthens the good estrogens and testosterone. Hormonal acne results from an imbalance of good estrogens, bad estrogens, and testosterone. If this sounds like you, you might benefit from DIM. Do you see your acne along the chin, jawline, or cheeks?.Is your acne the deep, painful, cystic variety that doesn’t easily pop? (Don’t try to pop it…but you know the kind of pimples these are.).Does your acne appear at the same time in your menstrual cycle each month?.Induce tumor cell death, preventing tumor cells from replicating ĭo you have hormonal acne? Here are a few telltale signs of hormonal acne:.Encourage estrogens to metabolize into the protective 2?OHE1.Researchers showed that DIM and its precursor, I3C, adjust your ratios of estrogen metabolites and protect your body in several ways: Related: Science-Backed Ways to Boost Low Libido & Sex Drive What DIM does to your estrogen metabolite ratio These estrogen metabolites are the ones responsible for all of the problems you may attribute to estrogen, including PMS, fibroids, endometriosis, water retention, acne, low sex drive and more. It deserves more scrutiny for its influence on cancer because of its ability to alter DNA without even hooking up to an estrogen receptor. If your estrogen metabolism favors 2-OHE1, you’re less likely to experience the negative effects of estrogen, including pre-menopausal and post-menopausal breast cancer Īlthough 4-hydroxyestrone (4-OHE1) gets far less research attention in estrogen studies, the research that is out there confirms it as a cancer-causing estrogen. Newer research takes it a step further, pointing out that it’s not the individual levels that matter - rather, it’s the ratio of good estrogen to bad estrogen. Levels of 16-alphy-hydroxy-estrone (16-OHE1), the “bad” estrogen, are elevated in women and research animals with breast cancer. Bad estrogens: 16-alpha-hydroxyestrone, 4-hydroxyestrone Proper cholesterol levels (in animal models) Ģ-OHE1 also serves as a strong antioxidant, protecting the body from damaging free radicals.Higher quality collagen in the skin and joints.Healthy levels of 2-OHE1 are associated with: So far, evidence points to 2-OHE1 as a cancer preventive. It’s tricky because so many other factors go into DNA damage and tumor formation. There’s a bit of controversy as to whether 2-hydroxyestrone (2-OHE1) causes cancer or prevents it. Related: Find Out If You’re Estrogen Dominant Now Good estrogen: 2-hydroxyestrone Certain estrogens have a positive action on the body, while others cause problems. It’s not enough to demonize all estrogens. “bad” estrogenĪ lot of women and a substantial portion of men are either aware or suspect they are estrogen dominant - they have too much estrogen relative to other hormones. Second, it converts bad estrogens into good estrogen metabolites. First, it blocks the enzyme that converts testosterone into estrogen. Xenoestrogens (estrogen imitators from your personal and household products and environment) still make their way inside your body as they would without DIM. Your body will continue to produce the estrogen it would have produced without DIM. You’ll see people using DIM as an estrogen blocker, but that’s not exactly how it works. Here are the more noteworthy findings around DIM so far. Science is emerging and the results are promising. Preventing negative effects of testosterone supplementation. There is science behind benefits of DIM for things like: The list of uses for diindolylmethane is growing as research on the topic expands. Keep reading to find out what DIM can do for weight loss, acne, menopause and more. The benefits of DIM go way beyond breast cancer prevention. If you take DIM in a capsule, you avoid those extra compounds and the resulting thyroid pitfalls. You can still have your broccoli and cabbage with a lazy thyroid. There’s a two-way cause-effect relationship between your thyroid and excess estrogen. If you have thyroid problems, you have to pay attention to goitrogens. The veggies that contain indole-3-carbinol are the same ones that contain goitrogenic compounds - compounds that mess with your thyroid. You could eat a giant serving bowl of broccoli and cabbage to get the researched dose of DIM, and veggies are obviously necessary for overall health. When indole-3-carbinol hits your stomach acid, a chemical reaction converts it to diindolylmethane (DIM), and that’s what works its magic. Remember when the buzz was that cruciferous vegetables (like broccoli, cabbage, cauliflower, etc.) help prevent breast cancer? That’s because they contain a compound called indole-3-carbinol.
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